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Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.
Ghorbani P, Kim SY, Smith TKT, Minarrieta L, Robert-Gostlin V, Kilgour MK, Ilijevska M, Alecu I, Snider SA, Margison KD, Nunes JRC, Woo D, Pember C, O'Dwyer C, Ouellette J, Kotchetkov P, St-Pierre J, Bennett SAL, Lacoste B, Blais A, Nair MG, Fullerton MD. Ghorbani P, et al. Among authors: kilgour mk. PLoS Pathog. 2023 Sep 25;19(9):e1011658. doi: 10.1371/journal.ppat.1011658. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37747879 Free PMC article.
Assessing the Immune Regulatory Role of Metabolites In Vitro.
McPhedran S, Choe J, MacPherson S, Kowalchuk G, Chan V, Kilgour MK, Lum JJ. McPhedran S, et al. Among authors: kilgour mk. Methods Mol Biol. 2023;2614:109-120. doi: 10.1007/978-1-0716-2914-7_8. Methods Mol Biol. 2023. PMID: 36587122
1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer.
Kilgour MK, MacPherson S, Zacharias LG, Ellis AE, Sheldon RD, Liu EY, Keyes S, Pauly B, Carleton G, Allard B, Smazynski J, Williams KS, Watson PH, Stagg J, Nelson BH, DeBerardinis RJ, Jones RG, Hamilton PT, Lum JJ. Kilgour MK, et al. Sci Adv. 2021 Jan 20;7(4):eabe1174. doi: 10.1126/sciadv.abe1174. Print 2021 Jan. Sci Adv. 2021. PMID: 33523930 Free PMC article.
Clinically relevant T cell expansion media activate distinct metabolic programs uncoupled from cellular function.
MacPherson S, Keyes S, Kilgour MK, Smazynski J, Chan V, Sudderth J, Turcotte T, Devlieger A, Yu J, Huggler KS, Cantor JR, DeBerardinis RJ, Siatskas C, Lum JJ. MacPherson S, et al. Among authors: kilgour mk. Mol Ther Methods Clin Dev. 2022 Feb 15;24:380-393. doi: 10.1016/j.omtm.2022.02.004. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2022. PMID: 35284590 Free PMC article.
Thermoneutral housing does not accelerate metabolic dysfunction-associated fatty liver disease in male or female C57Bl/6J mice fed a Western diet.
Nunes JRC, Smith TKT, Ghorbani P, O'Dwyer C, Trzaskalski NA, Dergham H, Pember C, Kilgour MK, Mulvihill EE, Fullerton MD. Nunes JRC, et al. Among authors: kilgour mk. Am J Physiol Endocrinol Metab. 2023 Jul 1;325(1):E10-E20. doi: 10.1152/ajpendo.00124.2023. Epub 2023 May 17. Am J Physiol Endocrinol Metab. 2023. PMID: 37196059